BioinformaticsOnline

We are currently looking to recruit a Microarray Data Analyst in the Clinical Sciences Centre (CSC)/Imperial College Microarray Centre based on the Hammersmith Hospital Campus of Imperial. The Microarray Centre (http://microarray.csc.mrc.ac.uk ), one of the leading academic microarray centres in the UK, carries out microarray research with over 200 Groups throughout the CSC and Imperial College and has responsibility for warehousing microarray data for three national and international research consortia. The Centre is the only translational medicine research centre in the UK for large scale Affymetrix-based clinical projects and a clinical data warehouse for mining and analysis of clinical microarray data is under development.

Role:
A vacancy has arisen Lonza biologics - Advanced Protein Technologies group (Cambridge-UK) for a Senior Scientist in Structural Bioinformatics / Computational Biochemistry to develop and expand its technology platform.
Key Responsibilities:
- Develop and run software tools required for protein aggregation analysis, protein stability, conformational characterisation and protein engineering.
- Design and implement modifications to existing tools to expand their current capabilities and throughput. Co-ordinate research activities with other members of APT as well as external collaborators and contractors to consolidate and enhance current in silico platform technology.

Role: A vacancy has arisen at Lonza Biologics - Advanced Protein Technologies group (Cambridge-UK) for a Research Scientist on Structural Bioinformatics / Computational Biochemistry to apply and develop its technology platform.
Key Responsibilities:
- Develop and run software tools required for protein aggregation analysis, protein stability, conformational characterisation and protein engineering.
- Implement modifications to existing tools to expand their current capabilities and throughput.
- Co-ordinate research activities with other members of APT as well as external collaborators and contractors to consolidate and enhance existing in silico platform technology.

DESCRIPTION:
We are looking for a Research Scienist who will be responsible for managing EMBL's participation within TAMAHUD, an EU project coordinated by Siena Biotech and aimed at identifying early disease markers, novel pharmacologically tractable Targets and small molecule phenotypic modulators in Huntington’s disease. State-of-the-art data integration approaches, such as pathway analysis and text mining will be applied to characterize potential signaling networks impacted by the HD mutation, which could provide additional candidate targets for pharmacological intervention for successive validation.

Bioinformatics support and development

Description
You have general bioinformatics experience and the capacity to understand client's needs. Furthermore, you have profound experience in data analysis and statistics, in particular in gene expression analysis. With great flexibility, you find adequate approaches to support a broad spectrum of users with different needs and levels of experience. You notice the importance of having "standard operational procedures" for the resolution of users concerns in a global context. You are committed to work with deadlines, objectives and within fast-evolving dynamic environments.

Data Mining and Pathway Reconstruction

Supervisors: Prof. Nils Peder Willassens (nils-peder.willassen@fagmed.uit.no) & Associate Professor Peik Haugen (peik.haugen@fagmed.uit.no), University of Tromsø – Norway, Protein Research Group (Http://cold.imb.fm.uit.no), Department of Molecular Biotechnology, Institute Of Medical Biology Dr. Jacob Köhler Rothamsted Research, Harpenden, UK / University of Tromsø (jacob.koehler@bbsrc.ac.uk)