BioinformaticsOnline

Based in the laboratory of Dr. Casey Bergman (Faculty of Life Sciences, University of Manchester, we seek a capable and enthusiastic computational biologist to study the evolution of gene expression in Drosophila as part of a HFSP-funded project in collaboration with Dr. Uwe Ohler (Duke University, Durham, USA) and Dr Pavel Tomancak (Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, DE). This project will involve the analysis of genome-wide sequence and expression data within and among species of Drosophila to gain insight into the evolutionary forces that control changes in transcriptional regulation across developmental stages.

Three postdoctoral fellowships in machine learning and computational biology are available in the lab of William Stafford Noble in the Department of Genome Sciences at the University of Washington, Seattle, WA, USA.

The Bioinformatics Unit in the Department of Computer Science at University College London invites applications for a BBSRC funded postdoctoral position to develop bioinformatics methods for the analysis and prediction of membrane protein structure. In particular, the work will involve building a pipeline for automatic modelling of transmembrane protein structures along with methods for assessing the quality of the models. A further aspect of the project will entail developing a database to make these models available to biologists along with integrated functional information. This post is part of a joint project with Prof. Janet Thornton at the European Bioinformatics Institute.

The Centre for Plant Integrative Biology (CPIB) within the University of
Nottingham has begun a five year programme to create a virtual root. This will
serve as an exemplar for Integrative Systems Biology in modelling multi-cellular
systems. CPIB is jointly funded by the BBSRC and EPSRC as part of their
initiative to establish a number of Centres for Integrative Systems Biology.
This project brings together biologists, engineers, mathematicians and computer
scientists to generate new data, biological resources and virtual models that
will aid the understanding of how plant roots grow and develop.

Postdoctoral Research Fellow: Gene Function Analysis and Development of Cisgenic Apples with Red Fruit Flesh. 4 years fulltime (40 hours).

Vacancynumber: Inova 01

Organization:
Inova Fruit B.V. is a young company that selects and develops new apple cultivars that fit perfectly in market segments. Inova Fruit B.V. prepares and co-ordinates the market introduction of these cultivars. Inova Fruit B.V. collaborates on molecular breeding of new apple cultivars with the Plant Science Group (PSG) of Wageningen University and Research Centre (WUR).

We are using genomic and bioinformatics approaches to investigate the molecular processes underlying mammalian stem cell differentiation and lineage commitment. Computational biologists are sought to participate in ongoing collaborations with experimental laboratories, and to lead new research projects in human and mouse embryonic and neural stem cell characterization.

The post holder will have the opportunity to initiate their own computational projects, but will also coordinate with colleagues in experimental labs and contribute to the design and execution of related studies. Projects will focus on large-scale gene expression profiling, comparative genomics and regulatory systems modelling.

The Bioinformatician/Ontologist will work within the Microarray Team at the EBI on the EU funded EMERALD project to develop an ontology of terms related to microarray data analysis and experiments. The successful applicant will report to the Curation Coordinator for the ArrayExpress database where the ontology will be applied. The ArrayExpress team is multi disciplinary and consists of approx. 20 Biologists, Curators, Software Developers, Ontologists and Computer Scientists who deliver the infrastructure and the data which together comprise one of the world?s largest microarray databases.

BACKGROUND:
A postdoctoral position in computational biology is available in the group of Dr. Paul Bertone at the EMBL European Bioinformatics Institute (EMBL-EBI) in Cambridge, England. We are using genomic and bioinformatics approaches to investigate the molecular processes underlying mammalian stem cell differentiation and lineage commitment. Computational biologists are sought to participate in ongoing collaborations with experimental laboratories, and to lead new research projects in human and mouse embryonic and neural stem cell characterization.