BioinformaticsOnline

University of Bologna, Italy

In the 9th edition of the Bologna Winter School in Bioinformatics, we will ask the question of what grand challenges Computational Biology and Bioinformatics will explore in the next decade. Different subjects focusing as a test case on the human genome, including genome annotation, biodiversity, alternative splicing and its regulation, epigenetics, information transfer from 1D to 3D genetic code, cellular function and simulation, genomic medicine, SNPs and maladies will be reviewed to highlight present results and future perspectives to cope with the requirement of integrating computation with molecular description to understand basic principles of Biology.